Intranasal challenge with aspirin in the diagnosis of aspirin intolerant asthma: evaluation of nasal response by acoustic rhinometry
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چکیده
منابع مشابه
Nasal Ketorolac Challenge Using Acoustic Rhinometry in Patients With Aspirin-Exacerbated Respiratory Disease.
BACKGROUND AND OBJECTIVE Safer and less time-consuming alternatives to single-blind placebo-controlled oral challenge (SBPCOC) have been sought for the diagnosis of aspirin-exacerbated respiratory disease (AERD). Nasal challenges with various nonsteroidal anti-inflammatory drugs and assessment methods have been developed. Objective: Our objective was to evaluate the utility and safety of nasal ...
متن کاملIntranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma.
INTRODUCTION Nasal polyposis associated with aspirin-intolerant asthma tends to be difficult to control, with frequent recurrences. We examined the effect of intranasal lysine-aspirin administration on resistant nasal polyps of asthmatic, aspirin-intolerant patients, when used in addition to routine therapy. PATIENTS AND METHODS Thirteen patients with asthma and intolerance to aspirin were re...
متن کامل287 Nasal Nitric Oxide Levels after Lysine Aspirin Nasal Challenge in Subjects with Aspirin Induced Asthma
100% and pansinusitis. They needed antibiotic scheme. At 2 years in 83.3% had a VAS.7. At 58.3% had pansinusitis. The bronchial relapse did not increase. We determined the presence of VAS. 7 and pansinusitis (OR 1⁄4 4). The bronchial relapse did not influence with increasing VAS (OR 1⁄4 1). Conclusions: Nasal symptoms persistent were secondary to the nasal polyps and pansinusitis with higher le...
متن کاملMontelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Aspirin-induced asthma (AIA) is associated with increased production of cysteinyl leukotrienes (CysLT). Although leukotriene CysLT1-receptor antagonists improve lower airway outcomes in AIA, their effects and dose-response in the upper airway is less well documented. The present study evaluated the dose-response for montelukast (ML) against nasal lysine-aspirin challenge in patients with AIA. A...
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ژورنال
عنوان ژورنال: Thorax
سال: 2000
ISSN: 0040-6376
DOI: 10.1136/thorax.55.11.921